Thymosin Beta 4
TB-500 (Thymosin Beta-4) is a naturally occurring peptide present in
almost all animal and human cells. TB500 is a synthetic peptide that has
been directly linked to recovery as it is plays a vital role in building new
blood vessels, new small muscle tissue fibers, cell migration and blood cell
reproduction. If you are an injured athlete, all of these properties are
something that becomes very desirable when looking to speed up the
TB-500 is a sterile, non-pyrogenic, white lyophilized powder intended for
subcutaneous or intramuscular injection, after reconstitution with sterile
Water for Injection.
Mechanism of Action
The main functionality of TB-500 hinges on the ability to up-regulate cell
building proteins like Actin. Up-regulation of Actin allows TB-500 to promote
cell migration and proliferation. This not only helps build new blood vessel
pathways but also regulates inflammation directly correlated with wound
healing. Its versatility even extends to its molecular structure and low
molecular weight, which lends to its mobility and ability to travel long
distances through tissues. This means when targeting injured areas
(chronic or acute), TB-500 has the ability to circulate the body and find
those areas of injury in order to take corrective action. Added benefits of
improved flexibility, reduced inflammation in tendons have been noticed,
and some users report some re-grown lost hair (also reports of grayed hair
In fact, studies are being done which correlate TB-500 with healing of the
heart, in some cases repairing ventricular hypertrophy.
The positive attributes of TB-500 include blood vessel and cell
differentiation, growth of new blood cells from pre-existing vessels in
dermal tissue, decreased inflammation and increase in flexibility. The flu
like symptoms or lethargy/head rush associated with most peptides does
not seem to be widely reported with TB500.
Instructions for reconstitution
Flip off the top of the peptide vial with your thumb. Use the alcohol swab to wipe the
rubber stopper of the peptide vial. Push the needle of the syringe into the middle of the
rubber stopper so it goes through the rubber and into the vial. Now, while angling the
needle so that the water for injection goes down the side of the glass, rather than
directly into the powder, inject the water for injection into the vial. Repeat this step until
you have the correct amount of water in the vial. The powder will dissolve quickly,
however it can help to gently roll the vial in between your fingers (do not shake the vial
vigorously). Remove the syringe and dispose of it. You should never re-use a syringe.
Recommended dosage of TB-500:
- 4 – 8mg of TB-500 per week for loading phase
- 2 – 6mg of TB-500 per 2 weeks for maintenance phase
- After reconstitution, may be stored for a maximum of 14 days in a refrigirator at 2°C — 8°C.
- Store vials in an upright position.
- Store in a refrigerator (2°C — 8°C). Keep in the outer carton in order to protect from light.
- For one month can be stored at room temperature.
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