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GHRP-6 (10 MG X 10 VIALS)

190.00

SKU: BP-P20 Category:

Description

GHRP-6

Growth Hormone Releasing Peptide-6

 

Description

GHRP-6 (Growth Hormone Releasing Peptide —6) is a hexapeptide with a

chain composed of 6 amino acids. It is one of several synthetic met-

enkephalin analogs that include unnatural D-amino acids that were

developed for their growth hormone releasing activity and are called growth

hormone secretagogues. GHRP-6 is a true HGH secretagogue.

This growth hormone releasing peptide is distinct from GHRH and do not

act at the GHRH receptor, but instead acts at the growth hormone

secretagogue receptor, now renamed as the ghrelin receptor.

 

GHRP-6 is a sterile, non-pyrogenic, white lyophilized powder intended for

subcutaneous or intramuscular injection, after reconstitution with sterile

Water for Injection.

 

Mechanism of Action

GHRP-6 is not an active fragment of growth hormone releasing hormone

(GHRH). Which means it stimulates the body’s own secretion of HGH.

Human Growth hormone has been shown in studies to promote lean body

mass and reduce adiposity (fat). This growth hormone releasing peptide is

distinct from GHRH and do not act the GHRH receptor, but instead acts at

the growth hormone secretagogue receptor, now renamed as the gh-relin

receptor.

GHRP-6’s special sequence is considered to provide a signal to the body to

begin secreting Growth Hormone(GH) release while also blocking

Somatostatin, a hormone that inhibits Growth Hormone release. Research

studies have shown that GHRP-6 stimulation of Growth Hormone has host

of beneficial effects such as decreased body fat, increased muscle, and

increased strength and stamina so maximizing the production and

secretion can be a great addition to improved animal physical shape.

Increased amounts of Growth Hormone then can cause the liver to secrete

the hormone IGF-1 which has also been implicated in improving the animal

body’s ability to burn fat and build muscle. Clinical cases have shown that

the use of GHRP-6 was associated with increased muscle mass and a

reduction of body fat.

GHRP-6 has been one of the most thoroughly studied and is believed to be

acting naturally on both pituitary and hypothalamic sites (Fairhall et al.

1995). This has been demonstrated in the primary pituitary cells of rats in a

time-dependent and dose-dependent manner. In another study of Fairhall

et al. (1995), they concluded that the major target of the GHRP-6 in vivo is

the hypothalamus after observing that the GH(Growth Hormone) release

induced by the central GHRP-6 administration is guinea pigs was inhibited

by the central action of somatostatin. Furthermore, an inhibition by

somatostatin with the activated GRF neurons (GRF=Growth Hormone

Releasing Factor), induced by GHRP-6, was observed via receptors known

to be located on or near the GRF themselves. However, it was also

observed that GHRP-6 had no effect on the intracellular cAMP levels unlike

that of GHRP-2. This particular experiment further indicated that GHRP-6 is

effectively stimulating GH release from somatotrophs through different

receptors, the mechanisms of which are not yet known (Chan et al. 1989).

However, some researchers suggest that action and efficiency of growth

hormone is dependent on the physical condition of the experimental unit. In

for example, GH secretion decreased with obesity.

 

This is contrary in the case of the GHRP-6 which showed increased (almost

twice that of GHRP) GH responses when administered in obese patients

(Cordido et al. 1993). Though obesity has shown affecting the efficiency of

the hormone, it was also suggested that GHRP-6’s effects, at least at the

dose-dependent manners, were found to be sex-and age-independent

without being affected by the adrenergic pathways using the a2

adrenergic receptors (Penalva et al. 2008).

 

Adverse reactions

GHRP-6 Peptide is generally very well tolerated by most individuals when

used at the recommended dosages of up to 200mcg per injection.

 

  • Water Retention
  • Tiredness
  • Increased Hunger

 

Instructions for reconstitution

Flip off the top of the peptide vial with your thumb. Use the alcohol swab to wipe the

rubber stopper of the peptide vial. Push the needle of the syringe into the middle of the

rubber stopper so it goes through the rubber and into the vial. Now, while angling the

needle so that the water for injection goes down the side of the glass, rather than

directly into the powder, inject the water for injection into the vial. Repeat this step until

you have the correct amount of water in the vial. The powder will dissolve quickly,

however it can help to gently roll the vial in between your fingers (do not shake the vial

vigorously). Remove the syringe and dispose of it. You should never reuse a syringe.

 

Dosage

Recommended dosage of GHRP-6:

  • 100mcg (0.10mg) once per day for anti-aging.
  • Between 400-600 mcgs, divided in two or three doses per day for

muscle gain and fat loss, directed via subcutaneous injections.

 

Storage

  • After reconstitution, may be stored for a maximum of 14 days in a

refrigerator at 2°C — 8°C.

  • Store vials in an upright position.
  • Store in a refrigerator (2°C — 8°C). Keep in the outer carton in order to

protect from light.

  • For one month can be stored at room temperature.

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